Johnson SC, Yanos ME, Kayser EB, Quintana A, Sangesland M, Castanza A, Uhde L, Hui J, Wall VZ, Gagnidze A, Oh K, Wasko BM, Ramos FJ, Palmiter RD, Rabinovitch PS, Morgan PG, Sedensky MM, Kaeberlein M (2013). mTOR Inhibition Alleviates Mitochondrial Disease in a Mouse Model of Leigh Syndrome. Science. 2013 Nov;. [Abstract] [Full Text]
Ramos FJ, Kaeberlein M, Kennedy BK (2012). Elevated MTORC1 signaling and impaired autophagy. Autophagy. 2013 Jan; 9(1):108-9.
Ramos FJ, Chen SC, Garelick MG, Dai DF, Liao CY, Schreiber KH, Mackay VL, An EH, Strong R, Ladiges WC, Rabinovitch PS, Kaeberlein M, Kennedy BK (2012). Rapamycin Reverses Elevated mTORC1 Signaling in Lamin A/C-Deficient Mice, Rescues Cardiac and Skeletal Muscle Function, and Extends Survival. Sci Transl Med. 2012 Jul; 4(144):144ra103.
Ramos FJ, Kaeberlein M (2012). Ageing: A healthy diet for stem cells. Nature. 2012 Jun; 486(7404):477-8.
Mehta R, Chandler-Brown D, Ramos FJ, Shamieh LS, Kaeberlein M (2010). Regulation of mRNA translation as a conserved mechanism of longevity control. Adv. Exp. Med. Biol.. 2010 ; 694:14-29.
Dong, L. Q., Ramos, F. J., Wick, M. J., Lim, M. A., Guo, Z. M., Strong, R., Richardson, A., and Liu, F. (2002). Cloning and characterization of a testis and brain-specific isoform of mouse 3 '-phosphoinositide-dependent protein kinase-1, mPDK-1 beta, Biochemical and Biophysical Research Communications 294, 136-144.
Langlais, P., Dong, L.Q., Ramos, F. J., Hu, D. R., Li, Y. H., Quon, M. J., and Liu, F. (2004). Negative regulation of insulin-stimulated mitogen-activated protein kinase signaling by Grb10, Molecular Endocrinology 18, 350-358.
Mao, X. M., Kikani, C. K., Riojas, R. A., Langlais, P., Wang, L. X., Ramos, F. J., Fang, Q. C., Christ-Roberts, C. Y., Hong, J. Y., Kim, R. Y., et al. (2006). APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function, Nature Cell Biology 8, 516-U165.
Mehta R, Chandler-Brown D, Ramos FJ, Shamieh LS, Kaeberlein M (2010). Regulation of mRNA translation as a conserved mechanism of longevity control. Adv. Exp. Med. Biol.. 2010 ; 694:14-29.
Mehta, R, Chandler-Brown, D, Ramos, FJ, Shamieh, LS, Kaeberlein, M. (2010) Regulation of mRNA translation as a conserved mechanism of longevity control. in Protein Metabolism and Homeostasis in Aging. N. Tavernarakis (Ed.)
Mehta, R., Steinkraus, K.A., Sutphin, G.L., Ramos, F.J., Shamieh, L.S., Huh, A., Davis, C., Chandler-Brown, D., Kaeberlein, M. (2009).Proteasomal Regulation of the Hypoxic Response Modulates Aging in C. elegans. Science 324, 1196-1198.
Ramos, F. J., Langlais, P. R., Hu, D. R., Dong, L. Q., and Liu, F. (2006). Grb10 mediates insulin-stimulated degradation of the insulin receptor: a mechanism of negative regulation, American Journal of Physiology-Endocrinology and Metabolism 290, E1262-E1266.
Wang C, Xin X, Xiang R, Ramos FJ, Liu M, Lee HJ, Chen H, Mao X, Kikani CK, Liu F, Dong LQ (2009). Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells. J Biol Chem. 284(46):31608-15.
Wang, L., Balas, B., Christ-Roberts, C. Y., Kim, R. Y., Ramos, F. J., Kikani, C. K., Li, C., Deng, C., Reyna, S., Musi, N., et al. (2007). Peripheral disruption of the grb10 gene enhances insulin signaling and sensitivity in vivo, Molecular and Cellular Biology 27, 6497-6505.
Wick, K. R., Werner, E. D., Langlais, P., Ramos, F. J., Dong, L. Q., Shoelson, S. E., and Liu, F. (2003a). Grb10 inhibits insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the insulin receptor, Journal of Biological Chemistry 278, 8460-8467.
Wick, M. J., Dong, L. Q., Riojas, R. A., Ramos, F. J., and Liu, F. (2000). Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1, Journal of Biological Chemistry 275, 40400-40406.
Wick, M. J., Ramos, F. J., Chen, H., Quon, M. J., Dong, L. Q., and Liu, F. (2003). Mouse 3-phosphoinositide-dependent protein kinase-1 undergoes dimerization and trans-phosphorylation in the activation loop, Journal of Biological Chemistry 278, 42913-42919.