Molecular Mechanisms of Aging

Research in the Kaeberlein Lab is focused on developing therapies for age-associated diseases by targeting the pathways that regulate aging.

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2017-12-06 The paths of mortality: how understanding the biology of aging can help explain systems behavior of single cells. Published in Curr Opin Syst Biol.
2017-09-09 Rapamycin treatment attenuates age-associated periodontitis in mice. Published in Geroscience.
2017-09-01 Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency. Published in Front. Genetics.
2017-07-13 A system to identify inhibitors of mTOR signaling using high-resolution growth analysis in Saccharomyces cerevisiae. Published in Geroscience.
2017-06-29 Inter-organ regulation of haem homeostasis. Published in Nat Cell Biol.
2017-04-03 A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs. Published in GeroScience
2017-03-29 "Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans" published in PLoS Genetics.

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