en UW Kaeberlein Lab Announcements Research in the Kaeberlein Lab is focused on developing therapies for age-associated diseases by targeting the pathways that regulate aging. Mon, 27 Mar 2017 02:32:51 -0600 Zend_Feed_Writer 1.11.6 (http://framework.zend.com) http://kaeberleinlab.org admin@kaeberleinlab.org (Admin) Admin 2017-03-08 press release. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2017-02-28 Asymptomatic heart valve dysfunction in healthy middle-aged companion dogs and its implications for cardiac aging" published in Geroscience. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2017-02-24 Systems biology approach to late-onset Alzheimer's disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments" published in Alzheimer's Dementia. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2017-02-21 CAN1 Arginine Permease Deficiency Extends Yeast Replicative Lifespan via Translational Activation of Stress Response Genes" published in Cell Reports. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2017-01-29 A review of the biomedical innovations for healthy longevity" published in Aging. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2017-01-18 Video of Dr. Kaeberlein's panel discussion at the Economist "Business of Longevity" conference. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-12-19 Dietary restriction and lifespan: Lessons from invertebrate models" published in Aging Research Reviews. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-10-26 Dog Aging Project Reddit AMA starting at 3 PM EST. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-10-11 Rapamycin enhances survival in a Drosophila model of mitochondrial disease" published in Oncotarget. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-10-10 Listen to the podcast. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-08-31 Listen to the interview here. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-08-29 Smithsonian Magazine interview with Daniel Promislow. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-08-26 Age-associated vulval integrity is an important marker of nematode healthspan" published in the Journal of the American Aging Association (AGE). ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-08-23 "Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice" published in eLife.  Full text here.
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2016-07-19 Rapamycin: A real fountain of youth?" ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-07-01 Rapamycin in aging and disease: maximizing efficacy while minimizing side effects" published in Oncotarget. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-07-01 New insights into cell non-autonomous mechanisms of the C. elegans hypoxic response" and "New functional and biophysical insights into the mitochondrial Rieske iron-sulfur protein from genetic suppressor analysis in C. elegans" published in Worm. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-06-24 Rapamycin: The Real Deal Anti-Aging Pill?" ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-06-07 The Takeaway. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-05-17 New York Times. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-05-05 Monique Ming Laven and KIRO TV visit the Kaeberlein lab to report on the Dog Aging Project.  See the video here.

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2016-05-03 The dog aging project: translational geroscience in companion animals" published in Mammalian Genome. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-05-02 UW Medicine Pulse podcast on the Dog Aging Project with Dr. Kaeberlein and Dr. Promislow. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-03-22 "Microfluidic Technologies for Yeast Replicative Lifespan Studies" published in Mechanisms of Ageing and Development. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-03-08 KIRO Radio's Ron and Don Show. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-02-23 Popular Science. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2016-01-13 Aneuploidy shortens replicative lifespan in Saccharomyces cerevisiae" published in Aging Cell. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-12-28 Christine Chen and Heather Huang on being awarded Mary Gates Research Scholarships. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-12-03 Healthy aging: The ultimate preventative medicine" published in Science as part of a Special Collection on the Biology of Aging.  Free text can be downloaded from our Publications Page. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-11-19 Cell nonautonomous activation of flavin-containing monooxygenase promotes longevity and health span" published in Science.  Free text can be downloaded from our Publications page. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-11-02 Biochemical Genetic Pathways that Modulate Aging in Multiple Species" published in Cold Spring Harb Perspect Med. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-10-27 Full text here. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-10-26 PNAS. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-10-12 A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging" published in Cell Metabolism. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-09-22 Systematic analysis of asymmetric partitioning of yeast proteome between mother and daughter cells reveals "aging factors" and mechanism of lifespan asymmetry" published in PNAS. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-09-09 KOMO TV News. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-08-26 Transcription errors induce proteotoxic stress and shorten cellular lifespan" published in Nature Communications. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-08-10 Dog Aging Project featured on King 5 New Day Northwest. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-07-22 Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice" published in Frotiers in Genetics of Aging.

 

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2015-07-16 HHMI Gilliam Fellowship. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-07-15 H3K36 methylation promotes longevity by enhancing transcriptional fidelity" published in Genes and Development. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-06-17 The Biology of Aging: Citizen Scientists and Their Pets as a Bridge Between Research on Model Organisms and Human Subjects" published in the Journal of Veterinary Pathology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-06-17 The Biology of Aging: Citizen Scientists and Their Pets as a Bridge Between Research on Model Organisms and Human Subjects" published in the Journal of Veterinary Pathology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-05-15 2015 Undergraduate Research Symposium. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-05-04 PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae" published in AGE, the journal of the American Aging Association.

 

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2015-04-29 Why Is Aging Conserved and What Can We Do about It?" published in PLoS Biology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-04-17 National Council on Undergraduate Research. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-02-26 Fertile waters for aging research" published in Cell. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2015-01-01 Syringaresinol protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1α in a FOXO3-dependent mechanism" published in Oncotarget. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-12-19 Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import" published in PLoS Genetics. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-12-05 Alison Leondard for being awarded a Mary Gates Research Scholarship! ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-12-04 Simon Johnson for winning the Science and SciLifeLab Translational Medicine prize for his essay "A target for pharmacological intervention in an untreatable human disease". ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-11-26 Dog Aging Project featured in Reuters video. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-11-17 Citizen science hopes to add healthier years to dog lives" featured in UW Health Science News. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-11-03 Dog Aging Project featured on the front page of the Seattle Times. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-10-31  Visit it today. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-10-29 Dog Aging Project featured in Nature News.  Donations to the Dog Aging Project can now be accepted through the UW Foundation. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-10-28 Symposium on Healthy Aging in People and Their Pets will be held at Hotel Deca, Seattle.  If you are interested in attending, you can register here. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-10-23 Alessandro Bitto and Jason Pitt to give the Genetic Approaches to Aging Trainee Research Presentations.  10/23 2:30-4 PM Foege N-130. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-10-13 Modulating mTOR in aging and health" published in Interdisciplinary Topics in Gerontology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-08-07 Rapamycin and ageing: When, for how long, and how much?" published in Journal of Genetics and Genomics. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-08-01 A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer" published in Dis Model Mech. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-07-30 http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-07-17 The SAGA Histone Deubiquitinase Module Controls Yeast Replicative Lifespan via Sir2 Interaction" published in Cell Reports. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-07-01 Rejuvenation: It's in Our Blood" published in Cell Metabolism. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-06-03 Inactivation of Yeast Isw2 Chromatin Remodeling Enzyme Mimics Longevity Effect of Calorie Restriction via Induction of Genotoxic Stress Response" published in Cell Metabolism. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-05-16 2014 Undergraduate Research Symposium: Vikram Akam, Christine Chen, Shiwen Chen, Michael Chung, Cindy Dong, Farzin Eshaghi, Bruce Huang, Conner Jarvie, Grace Kim, Jane Kwon, Alison Leonard, Maryann Li, Margarete Moore, Billie Ocampo, Nic LeTexie, Nick Rintala, Nathan Schurman, Sarah Stanton, Iryna Strenytska, Elissa Sutlief, Ben Zipkin ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-04-21 Why we age". ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-04-17 Cindy Dong for being awarded a pretigious Mary Gates Research Scholarship and acceptance to the Univerity of Washington nursing program. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-03-26 Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans" published in Nature Communications. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-02-13 The mitochondrial unfolded protein response and increased longevity: Cause, consequence, or correlation?" published in Experimental Gerontology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-02-02 Seattle Seahawks defeated the Denver Broncos 43-8 in Super Bowl XLVIII.  Thanks for the great season and for bringing Seattle its first Super Bowl victory.  Go Hawks! ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-02-01 Oxygen and aging" published in the Annual Review of Gerontology and Geriatrics. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-01-31 Chemical warfare in the battle of the sexes" published in Science. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-01-30 Nar1 deficiency results in shortened lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutase" published in Mechanisms of Ageing and Development. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-01-10 course website and discussion list for additional details. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2014-01-07 Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response" published in PLoS Genetics.

 

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2013-12-18 Nathan Schurman and Jane Kwon for each being awarded a 2014 Mary Gates Research Scholarship. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-12-10 UV-Photoconversion of ethosuximide into a potent nematode toxin" published in PLoS One. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-11-26 mTOR Inhibition: From Aging to Autism and Beyond" published in Scientifica. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-11-14 mTOR Inhibition Alleviates Mitochondrial Disease in a Mouse Model of Leigh Syndrome" published in Science.  Read the UW news release here. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-11-13 Preserving Youth: Does Rapamycin Deliver?" published in Science Translational Medicine. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-10-29 Aging Research: The Latest Biomedical Perspectives" hosted by the American Federation for Aging Research. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-10-15 Yeast replicative aging: A paradigm for defining conserved longevity interventions" published in FEMS Yeast Research. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-10-15 Buffering the pH of the culture medium does not extend yeast replicative lifespan" published in F1000 Research. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-09-30 Deciphering the role of natural variation in age-related protein homeostasis" published in BMC Biology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-08-22 The ribosomal protein rpl22 controls ribosome composition by directly repressing expression of its own paralog, rpl22l1" published in PLoS Genetics. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-08-19 Dr. Simon Johnson on his successful Ph.D. thesis defense.  We wish him the best as he begins in post-doctoral research with Dr. Yousin Suh at Albert Einstein Medical College. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-07-11 Molecular mechanisms underlying genotype-dependent responses to dietary restriction" published in Aging Cell. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-05-16 Kaeberlein Lab undergraduates to present at the 2013 University of Washington Undergraduate Research Symposium.

Poster session 1 (11:00 AM to 12:30 PM): Xiaoli Wu, Alison Leonard, Hillary Miller.  

Oral session 1 (1:15 PM to 2:45 PM): Shannon Klum, Hillary Miller, Maya Sangesland, Melissa Primitivo, Heather Schneider.

Poster session 3 (2:30 PM to 4:00 PM): Jessica Hui.

Poster session 4: (4:15 PM to 5:45 PM): Yiyi Zhang, Jingyi Dong, Ashley Tonge, Jane Kwon, Janice Khoo, Malika Jhawar, Alex Van-Den-Ende, Alysha Dhami, Ha Doan

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2013-04-12 UW Medicine Online News. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-04-10 Congratulations to the following Kaeberlein Lab undergraduates on acceptance of admission into Ph.D. programs:

Marissa Fletcher - Massachusetts Institute of Technology, Biology

Sean Higgins - University of California, Berkeley, Molecular & Cell Biology 

Shannon Klum - Scripps Research Institute, Kellog School of Science and Technology 

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2013-03-09 "A Natural Polymorphism in rDNA Replication Origins Links Origin Activation with Calorie Restriction and Lifespan" published in PLoS Genetics.

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2013-03-04 Longevity and aging" published in F1000 Prime Reports. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-02-27 Molecular Biology of Aging Summer Course at Woods Hole this summer is March 11, 2013.  Directed by Dr. Kaeberlein and Dr. Daniel Promislow, this is a  

three-week lecture and laboratory course featuring the newest and most exciting ideas in aging research, with emphasis on molecular approaches.  All costs of attending the course are paid for by the Ellison Medical Foundation.  

For further information and application forms, visit: http://hermes.mbl.edu/education/courses/special_topics/bag.html

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2013-02-26 WormFarm: A quantitative control and measurement device towards automated C. elegans aging analysis" published in Aging Cell.

 

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2013-02-21 Drugs to slow aging are a matter of when, not if". ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-02-20 "Life-Span Extension From Hypoxia in Caenorhabditis elegans Requires Both HIF-1 and DAF-16 and Is Antagonized by SKN-1" published in J. Geronology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2013-01-21 End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging" published in FEMS Yeast Research.

 

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2013-01-18 mTOR is a key modulator of ageing and age-related disease" published in Nature. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-12-17 Mary Gates Research Scholarships! ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-12-09 Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae" published in Experimental Gerontology.

 

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2012-12-05 "Resveratrol Rescues SIRT1-Dependent Adult Stem Cell Decline and Alleviates Progeroid Features in Laminopathy-Based Progeria" published in Cell Metabolism. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-12-01 Longevity and Healthspan. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-11-30 Genome-Wide RNAi Longevity Screens in Caenorhabditis elegans" published in Current Genomics. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-11-20 Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging" published in Aging Cell. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-10-18 2012 Vincent J. Cristofalo Lectureship at the University of Pennsylvania. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-10-12 Elevated MTORC1 signaling and impaired autophagy" published in Autophagy. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-10-01 Dr. Adrienne Wang on being appointed to the Genetic Approaches to Aging Training Grant. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-09-04 22nd IUBMB 37th FEBS conference in Seville, Spain. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-08-15 pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast" published in Cell Cycle. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-07-26 Yeast as a model to understand the interaction between genotype and the response to calorie restriction" published in FEBS Letters. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-07-25 Rapamycin Reverses Elevated mTORC1 Signaling in Lamin A/C-Deficient Mice, Rescues Cardiac and Skeletal Muscle Function, and Extends Survival" published in Science Translational Medicine. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-07-12 Aging, Metabolism, Stress, Pathogenesis, and Small RNAs conference. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-07-03 Replicative and Chronological Aging in Saccharomyces cerevisiae" published in Cell Metabolism. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-06-27 Ageing: A healthy diet for stem cells" published in Nature. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-05-25 http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-05-18 UW Undergraduate Research Symposium.  Marissa Fletcher, Shannon Klum, Melissa Primitivo, Heather Schneider and Marissa Simko gave oral presentations.  Elroy An, Emma Bishop, Sean Higgins, Jessica Hui, Monika Jelic, Ki-Soo Jeong, Jilly Kim, Shannon Klum, Winston Lo, Hillary Miller, Dillon Pruett, Alex Schuster, Marissa Simko, Natalie Trongtham, Helen Vander Wende, and Pranav Venkataraman presented posters.  Pictures on Facebook. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-04-28 Northwest Biology Instructors' Organization Conference. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-04-16 Midlife gene expressions identify modulators of aging through dietary interventions" published in PNAS. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-03-13 Hypertrophy and senescence factors in yeast aging" published in FEMS Yeast Research. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-03-12 Mary Gates Research Scholarship! ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-02-29 Ribosome deficiency protects against ER stress in Saccharomyces cerevisiae" published in Genetics. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-01-09 A new chronological survival assay in mammalian cell culture" published in Cell Cycle. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2012-01-06 course webpage for locations and course materials.  ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-12-05 Mary Gates Research Scholarship! ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-12-02 Science Magazine News Focus on Sirtuins.  ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-11-21 The MDT-15 Subunit of Mediator Interacts with Dietary Restriction to Modulate Longevity and Fluoranthene Toxicity in Caenorhabditis elegans" published in PLoS One. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-11-19 Gerontological Society of America. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-11-19 Genome-wide analysis of yeast aging" published in Subcell Biochem. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-09-21 Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila" published in Nature. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-09-19 Composition and acidification of the culture medium influences chronological aging similarly in vineyard and laboratory yeast" published in PLoS One. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-09-16 schedule of talks. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-09-10 Sir2 deletion prevents lifespan extension in 32 long-lived mutants" published in Aging Cell. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-09-07 Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae" published in PLoS Genetics. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-08-23 http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-07-21 Trinations Aging Symposium" meeting report published in Mechanisms of Ageing and Development. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-06-16 Summit on Systems Biology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-06-11 http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-06-04 American Aging Association Annual Meeting in Raleigh, North Carolina.  Joe Delany, Devon Chandler-Brown, and Simon Johnson will present posters at the conference.  ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-05-30 Kaeberlein Lab Facebook Page. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-05-20 2011 University of Washington Undergraduate Research Symposium. Devon Chandler-Brown, Heather Schneider, and Eric McCarthy will give platform presentations.  Umema Ahmed, Emma Bishop, Ani Begun, Sylvia Sim, Monika Jelic, Elroy An, Annie Chou, Natalie Trongtham, Rick Moller, Pranav Venkataraman, Jilly Kim, Marissa Simko, Marissa Fletcher, Melissa Primitivo, Sean Higgens, Minnie Singh, and Dilreet Rai will present posters.   ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-05-10 Yeast as Models and Tools Symposium in Madrid, Spain.  The symposium is sponsored by the Fundacion Ramon Areces. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-05-06 2011 recipient of the Vincent Cristofalo “Rising Star” Award in Aging Research from the American Federation for Aging Research.  ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-04-29 1st Tri-Nations' Aging Symposium held at Guangdong Medical College in Dongguan, China.
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2011-04-02 A genomic analysis of chronological longevity factors in budding yeast" published in Cell Cycle. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-03-10 Model Systems of Aging conference in Cologne, Germany. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-03-08 The molecular basis and modification of the aging process" conference in Amsterdam.
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2011-03-03 Sageweb has a whole new look.  Check it out! ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-03-01 http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2011-01-17 HIF-1 modulates longevity and healthspan in a temperature-dependent manner" published in Aging Cell.
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http://kaeberleinlab.org/news http://kaeberleinlab.org/news
2011-01-01 Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast" published in Cell Cycle. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-12-22 Hot topics in aging research: protein translation and TOR signaling, 2010" published in Aging Cell. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-11-25 Restoration of senescent human diploid fibroblasts by modulation of the extracellular matrix" published in Aging Cell. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-11-21 Gerontological Society of America Annual Meeting in New Orleans. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-11-18 American Society of Nephrology meeting on TOR Signaling in Aging. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-10-01 Regulation of mRNA translation as a conserved mechanism of longevity control" published in Adv Exp Med Biol. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-08-13 The hypoxia inducible factor HIF-1 functions as both a positive and negative modulator of aging" published in Biological Chemistry. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-07-06 Kaeberlein Lab Facebook Page. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-06-25 A role for SIRT1 in the hypoxic response" published in Molecular Cell. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-06-01 UW Nathan Shock Center of Excellence in the Basic Biology of Aging. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-04-04 Devon Chandler-Brown named a 2010 Goldwater Scholar.   ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-03-25 Lessons on longevity from budding yeast" published in Nature. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-03-18 YODA: Software to facilitate high-throughput analysis of chronological life span, growth rate, and survival in budding yeast" published in BMC Bioinformatics. YODA can be accessed through SAGEWEB. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-02-11 Time magazine. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-01-26 Osher Lifelong Learning Institute course OLL106962 "Why we age: New insights into the molecular causes of aging" meets Tuesdays at 10 AM in FSH 102.  If you are enrolled in the course, click here to go to the course website. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-01-25 Regulation of mRNA Translation as a Conserved Mechanism of Longevity Control" published in the book Protein Metabolism and Homeostasis in Aging edited by Nektarios Tavernarakis.   ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2010-01-21 Resveratrol and rapamycin: are they anti-aging drugs?" published in BioEssays. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-12-23 U.S. News and World Report.   ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-12-21 Devon Chandler-Brown on receiving a Mary Gates Research Scholarship for the second consecutive year. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-12-21 Ben Dulken for receiving a Mary Gates Research Scholarship. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-11-05 Spermidine surprise for long life" published in Nature Cell Biology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-10-31 Guangdong Medical College in Dongguan, China. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-10-15 Science in Medicine Lecture by Dr. Kaeberlein.  "Molecular mechanisms linking diet, disease, and aging". ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-10-02 Aging is RSKy business" published in Science. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-10-02 course website. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-10-01 Podcast with Dr. Kaeberlein speaking on aging-related research from the Tufts Human Nutrition Research Center on Aging. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-09-26 Attenuation of Age-Related Metabolic Dysfunction in Mice With a Targeted Disruption of the C{beta} Subunit of Protein Kinase A" published in Journal of Gerontology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-09-11 Hot Topics in Aging Research: Protein Translation, 2009" published in Aging Cell. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-08-03 SETI radio. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-08-01 The hypoxic response and aging" published in Cell Cycle. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-07-08 A midlife longevity drug" published in Nature.  This News and Views provides perspective on the recent report that the TOR inhibitor rapamycin increases life span in mice.  Also see the UW press release "Longevity Pill on the Horizon". ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-06-25 Measuring replicative lifespan in the budding yeast" published in the Journal of Visualized Experiments. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-06-19 The TOR pathway comes of age", a comprehensive review on the role of TOR signaling in aging, published in Biochim. Biophys. Acta. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-06-15 "A genomic approach to yeast chronological aging" published in Methods in Molecular Biology ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-06-11 "Histone H4 lysine 16 acetylation regulates cellular lifespan" published in Nature ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-05-15 Undergraduate Mentor Award ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-05-15 Undergraduate Research Symposium ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-05-12 Quantifying Yeast Chronological Life Span by Outgrowth of Aged Cells and Measuring Caenorhabditis elegans Life Span on Solid Media published by Journal of Visualized Experiments ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-04-16 "Proteasomal Regulation of the Hypoxic Response Modulates Aging in C. elegans" published in Science. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-04-15 annual meeting on April 17th. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-03-15 "A molecular mechanism of chronological aging in yeast" published in Cell Cycle. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2009-03-04 http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-12-25 Kaeberlein Lab Facebook Group is on-line. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-11-25 Shortest-path network analysis is a useful approach toward identifyinggenetic determinants of longevity." published in PLoS One. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-09-09 sirtuins as therapeutic targets for age-associated disease at the 44th Annual Meeting of the European Association for the Study of Diabetes in Rome, Italy. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-09-08 Hot topics: Protein translation 2008" published in Aging Cell. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-08-07 A molecular age barrier" published in Nature. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-08-01 2008 New Scholar in Aging Award from the Ellison Medical Foundation. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-07-02 The ongoing saga of sirtuins and aging" published in Cell Metabolism. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-06-20 Erika Korinke and Stephanie Ortman! Both will be beginning medical school in the fall. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-06-02 Nathan Shock Centers of Excellence in Basic Biology of Aging Symposium at the 2008 American Aging Association Annual Meeting ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-05-16 Kaeberlein Lab undergraduates presented research at the 2008 University of Washington Undergraduate Research Symposium. Posters: Christina Davis, Alex Huh, Erika Korinke, Anna Le, Jenny Sagar. Platform Presentation: Brynn Lydum. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-05-08 Alex Huh selected as a 2008 NASA Space Grant recipient. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-05-07 Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans" published in BMC Developmental Biology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-04-17 Yeast lifespan extension by depletion of 60S ribosomal subunits is mediated by Gcn4" published in Cell. See the press release. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-03-15 Alzheimer's Association Western and Central Washington State Chapter 8th Annual Gala Dinner and Auction, "An Evening to Remember". More than $150,000 was raised to support research in the Kaeberlein lab toward developing therapies to prevent Alzheimer's disease. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-03-13 Quantitative evidence for conserved longevity pathways between divergent eukaryotic species" published on-line in Genome Research . See the press release. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-03-12 Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in C. elegans published early on-line in Aging Cell. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-02-27 A high-throughput quantiative analysis of yeast chronological life span" published in the Journal of Gerontology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2008-01-10 PATH501 "Molecular Mechanisms Linking Diet, Disease, and Aging" meets each Friday during Winter Quarter from 3:30-5PM in I-132. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2007-11-26 Undergraduate researchers Alex Huh, Erika Korinke, and Brynn Lydum received the prestigious Mary Gates Scholar Award. They join past Kaeberlein Lab Mary Gates Scholars, Brynn Lydum and Joe Jardine. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2007-11-17 Gerontological Society of America Annual Meeting in San Francisco. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2007-11-14 National Academies Keck Futures Initiatives on "The Future of Human Healthspan" from November 14th-17th. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2007-11-13 Buck Institute Symposium on "Nutrient Signaling and Aging". ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2007-11-12 Experimental Gerontology. ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2007-10-21 New Horizons in Science Briefing ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2007-09-14 Aging Cell ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2007-09-02 Molecular Basis of Aging" published early online at EMBO Reports ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news 2007-07-17 ABC News Nightline in a story discussing the potential of resveratrol for human health ]]> http://kaeberleinlab.org/news http://kaeberleinlab.org/news